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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA6 All Species: 32.73
Human Site: S88 Identified Species: 45
UniProt: Q15084 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15084 NP_005733.1 440 48121 S88 V D A D K H H S L G G Q Y G V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001095159 524 57323 S172 V D A D K H Q S L G G Q Y G V
Dog Lupus familis XP_532876 440 48280 S88 V D A D K H Q S L G G Q Y G V
Cat Felis silvestris
Mouse Mus musculus Q922R8 440 48082 S88 V N A D K H Q S L G G Q Y G V
Rat Rattus norvegicus Q63081 440 48155 S88 V N A D K H Q S L G G Q Y G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505713 415 44653 N84 K I F G A N K N K P E D Y Q G
Chicken Gallus gallus Q8JG64 505 56163 N88 V D C T A N S N T C N K Y G V
Frog Xenopus laevis NP_001086643 442 47765 S88 V N A D Q H Q S L G G Q Y G V
Zebra Danio Brachydanio rerio NP_922915 440 48022 S88 V D A D Q H N S L G G Q Y G V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 W128 Q A A D I I A W V T K K T G P
Honey Bee Apis mellifera XP_395981 427 47177 S84 I N A D E H K S L G A K Y G I
Nematode Worm Caenorhab. elegans Q11067 440 47710 S87 V D M T Q H Q S V G G P Y N V
Sea Urchin Strong. purpuratus XP_790496 399 42463 A76 K G V V K V G A V D M D V H S
Poplar Tree Populus trichocarpa XP_002320494 404 43880 P81 E Y G I R G F P T I K V F V P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22263 361 39478 G38 D S F E K E V G K D K G A L V
Baker's Yeast Sacchar. cerevisiae Q12404 318 36390
Red Bread Mold Neurospora crassa Q92249 369 39263 F45 G K P T L V E F F A P W C G H
Conservation
Percent
Protein Identity: 100 N.A. 82.8 94.5 N.A. 95.4 94.7 N.A. 81.1 20.7 82.3 76.1 N.A. 21.5 59.3 55.6 47
Protein Similarity: 100 N.A. 83.4 97.5 N.A. 97.9 97.5 N.A. 86.8 38.4 92 88.8 N.A. 38.9 76.3 73.4 63.8
P-Site Identity: 100 N.A. 93.3 93.3 N.A. 86.6 86.6 N.A. 6.6 33.3 80 86.6 N.A. 20 53.3 53.3 6.6
P-Site Similarity: 100 N.A. 93.3 93.3 N.A. 93.3 93.3 N.A. 20 53.3 93.3 100 N.A. 33.3 86.6 66.6 20
Percent
Protein Identity: 44.3 N.A. N.A. 31.1 23.8 31.1
Protein Similarity: 63.1 N.A. N.A. 47.9 39.7 48.4
P-Site Identity: 0 N.A. N.A. 13.3 0 6.6
P-Site Similarity: 13.3 N.A. N.A. 20 0 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 53 0 12 0 6 6 0 6 6 0 6 0 0 % A
% Cys: 0 0 6 0 0 0 0 0 0 6 0 0 6 0 0 % C
% Asp: 6 36 0 53 0 0 0 0 0 12 0 12 0 0 0 % D
% Glu: 6 0 0 6 6 6 6 0 0 0 6 0 0 0 0 % E
% Phe: 0 0 12 0 0 0 6 6 6 0 0 0 6 0 0 % F
% Gly: 6 6 6 6 0 6 6 6 0 53 48 6 0 65 6 % G
% His: 0 0 0 0 0 53 6 0 0 0 0 0 0 6 6 % H
% Ile: 6 6 0 6 6 6 0 0 0 6 0 0 0 0 6 % I
% Lys: 12 6 0 0 42 0 12 0 12 0 18 18 0 0 0 % K
% Leu: 0 0 0 0 6 0 0 0 48 0 0 0 0 6 0 % L
% Met: 0 0 6 0 0 0 0 0 0 0 6 0 0 0 0 % M
% Asn: 0 24 0 0 0 12 6 12 0 0 6 0 0 6 0 % N
% Pro: 0 0 6 0 0 0 0 6 0 6 6 6 0 0 12 % P
% Gln: 6 0 0 0 18 0 36 0 0 0 0 42 0 6 0 % Q
% Arg: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 6 0 0 0 0 6 53 0 0 0 0 0 0 6 % S
% Thr: 0 0 0 18 0 0 0 0 12 6 0 0 6 0 0 % T
% Val: 53 0 6 6 0 12 6 0 18 0 0 6 6 6 59 % V
% Trp: 0 0 0 0 0 0 0 6 0 0 0 6 0 0 0 % W
% Tyr: 0 6 0 0 0 0 0 0 0 0 0 0 65 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _